CDCRI San Diego July 12, 2017 Eczema What’s the Difference Between ATOPIC DERMATITIS and ECZEMA? CDCRI San Diego July 12, 2017 Eczema While atopic dermatitis and eczema are very similar skin ailments, they have some key differences. We compare and contrast atopic dermatitis vs. eczema to help you learn the differences and similarities.